Knowledge on rare diseases and related disorders are lacking among medical professionals across Africa. Rare Diseases are not integral part of the training of medical professionals in developing countries like most African countries hence making it difficult to identify, diagnose and manage rare diseases. Rare Disease ghana Initiative has collaborated with FYMCA Medicals Ltd to train medical professionals in Ghana. The trainings are CME accredited and provided through an in person face to face and an e-learning modules. So far, 8 medical professionals from Ghana have benefitted from this training. FYMCA Medicals Ltd is a UK based Organisation with the mission to develop improved rare disease education and services for those in the developing world.